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For patients such as those treated on RTOG with primary chemoradiation, detailed nomograms have been derived from that dataset combined with RTOG , enabling prediction of outcome based on a large number of variables. The risk of regional cancer recurrence after neck dissection is often estimated [] from a large series based on all upper aerodigestive squamous cell cancers. In this series, the overall risks at three years by pathological stage AJCC 7 were: [].

In , squamous cell cancer of the head and neck region was the fifth most common cancer other than skin cancer, globally, with an annual incidence of , cases and about 60, cases annually in the United States and Europe.

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The highest incidence age group was 60—69, and was higher in Caucasians than in other races. This in turn may overestimate the severity of the disease status. There has been a global trend in increasing OPC incidence, particularly in North America and northern Europe, but even in Taiwan, which has a very high rate for all cancers of the head and neck region, OPC rates increased increased more rapidly between and than any other cancer site.

From Wikipedia, the free encyclopedia. Anatomy of oropharynx and surrounding structures. Main article: HPV-associated oropharyngeal cancer awareness and prevention. At five years, locoregional control was improved with chemotherapy but adverse events were greater. Distant metastases were not affected. Low risk is T1-T2 N0-N1 with negative margins. A systematic review of HPV prevalence per oropharyngeal sub-site the last 3 years". Papillomavirus Research. Journal of Clinical Oncology Review. Lindberg, Robert June Mehanna, H. BMJ Editorial. Nguyen, N.

Opportunities and challenges for human papillomavirus vaccination in cancer

QJM Review. Psyrri, A. Current Opinion in Oncology Review. Emerging Infectious Diseases Review. Westra, W. Head and Neck Pathology Review.

HPV and Cervical Cancer: 25 Years from Discovery to Vaccine

February 3, Current Oncology Reports. Agoston, E. American Journal of Clinical Pathology. Ault, KA Infectious Diseases in Obstetrics and Gynecology. Chung, C. Clinical Cancer Research. February Acta Histochemica. Journal of Clinical Oncology. Elmofty, S. Gillison, M. May Journal of the National Cancer Institute. Frisch, M. The Lancet Submitted manuscript. Guan, X.

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The Lancet Oncology. Guy; Lee, C. Soon; Rose, Barbara February Radiotherapy and Oncology. Howard, Jason D.

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July Seminars in Radiation Oncology. Jung, A. International Journal of Cancer. Klussmann, J. Mar January Sexually Transmitted Diseases. Lajer, C. Lassen, P. Lawrence, Michael S. Bibcode : Natur.

Lohavanichbutr, P. Feb Mannarini, L. Acta Otorhinolaryngologica Italica. Martinez, I. Jan Maslon, Magda M. September Trends in Cell Biology. Robinson, M. Oral Oncology. Schlecht, N. Nov The Journal of Pathology. Seiwert, Tanguy Y. Smeets, S. Journal of Clinical Pathology.

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International Journal of Oral Surgery. Underbrink, M. Acta Oto-Laryngologica. Vidal, L. Hematology Oncology Clinics of North America. Weinberger, P. Sep Otolaryngology—Head and Neck Surgery. International Journal of Oncology.

A review of methods for detect human Papillomavirus infection | Virology Journal | Full Text

Nature Reviews Cancer. The Laryngoscope.

Keane, Florence K. Lydiatt, William M. March April Porceddu, Sandro V April The Lancet Oncology Editorial. Treatment [ edit ] Brockstein, Bruce E. Nature Reviews Clinical Oncology.